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[50-53] Although the precise mechanism of action of smoke ingredients is still under investigation, all proposed hypotheses state that the main effects of smoking on cardiovascular function are associated with the direct or indirect action of nicotine on the neuroregulation of the circulatory system, wherein sympathetic activity is increased and parasympathetic activity is reduced ( Figure 1 )

Specs High-quality print reproduction Article number: 200218 Brand: Van Gogh Museum Amsterdam Width: 30 cm Height: 40 cm Weight: 80 gram Material: 250 grams HV silk MC

[37:32] Sean We had the best day of my life